The Grandfield Research Group focuses on the development and characterization of biomaterials for bone implant devices, such as dental and orthopaedic devices. Our research is pioneering the investigation of biointerphases within mineralized tissues and at synthetic materials with multi-dimensional and high-resolution microscopies, including electron and atom probe tomography. Projects within the Biointerfaces Institute focus on materials development and evaluation of biocompatibility of surface functionalized titanium implant systems for dental and orthopaedic applications. The insights made through this work are contributing to the design of novel materials for improved implant success, and improved understanding of healthy and pathological bone.