Surface Plasmon Resonance (SPR) is an established tool that offers a new generation of label-free biomolecular analysis. It can provide information on kinetic processes (association and dissociation), binding affinity, analyte concentration and real-time molecule detection. SPR imaging (SPRi) is a sensitive label-free method of visualizing the whole of the biochip with a CCD camera. This enables the biochips to be prepared in an array format.